Timothy V Olah: search on Z-Library

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1

Bioanalytical strategies for developing highly sensitive liquid chromatography/tandem mass spectrometry based methods for the peptide GLP-1 agonists in support of discovery PK/PD studies

Hongwei Zhang, Baomin Xin, Christian Caporuscio, Timothy V. Olah

Journal:

Rapid Communications in Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

2

A bioanalytical strategy utilizing dried blood spot sampling and LC–MS/MS in discovery toxicology studies

Discenza, Lorell, Obermeier, Mary T, Westhouse, Richard, Olah, Timothy V, D’Arienzo, Celia J

Journal:

Year:

2012

Language:

english

File:

PDF, 680 KB

english, 2012

3

Beyond classical derivatization: analyte ‘derivatives’ in the bioanalysis of endogenous and exogenous compounds

Barnaby, Omar S, Benitex, Yulia, Cantone, Joseph L, McNaney, Colleen A, Olah, Timothy V, Drexler, Dieter M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

4

Immunoaffinity enrichment LCâMS/MS quantitation ofÂ CDH17 in tissues

Caporuscio, Christian, Holmes, Derek, Olah, Timothy V, Shipkova, Petia

Journal:

Year:

2020

File:

PDF, 1.15 MB

2020

5

Mechanistic investigation of ionization suppression in electrospray ionization

Richard King, Ryan Bonfiglio, Carmen Fernandez-Metzler, Cynthia Miller-Stein, Timothy Olah

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

6

Influence of β-adrenoceptor antagonists on the pharmacokinetics of rizatriptan, a 5-HT1B/1D agonist: differential effects of propranolol, nadolol and metoprolol

Michael R. Goldberg, David Sciberras, Marina De Smet, Richard Lowry, Lisa Tomasko, Yih Lee, Timothy V. Olah, Jamie Zhao, Kamlesh P. Vyas, Rita Halpin, Prasad H. Kari, Ian James

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

7

Synthesis of Conformationally Constrained 5,6,7,8-Tetrahydroimidazo[1,5-a]pyridine Inhibitors of Farnesyltransferase

Dinsmore, Christopher J., Zartman, C. Blair, Baginsky, Walter F., O'Neill, Timothy J., Koblan, Kenneth S., Chen, I-Wu, McLoughlin, Debra A., Olah, Timothy V., Huff, Joel R.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 56 KB

english, 2000

8

Location of Increased Serum Survival Gene and Selected Virulence Traits on a Conjugative R Plasmid in an Avian Escherichia coli Isolate

Timothy J. Johnson, Catherine W. Giddings, Shelley M. Horne, Penelope S. Gibbs, Richard E. Wooley, Jerod Skyberg, Pam Olah, Ronda Kercher, Julie S. Sherwood, Steven L. Foley and Lisa K. Nolan

Journal:

Year:

2002

Language:

english

File:

PDF, 1.97 MB

english, 2002

9

A strategy for liquid chromatography/tandem mass spectrometry based quantitation of pegylated protein drugs in plasma using plasma protein precipitation with water-miscible organic solvents and subsequent trypsin digestion to generate surrogate peptides for detection

Steven T. Wu, Zheng Ouyang, Timothy V. Olah, Mohammed Jemal

Journal:

Rapid Communications in Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

10

Optimization of Exactive Orbitrap™ acquisition parameters for quantitative bioanalysis

Wong, Richard L, Xin, Baomin, Olah, Timothy

Journal:

Year:

2011

Language:

english

File:

PDF, 614 KB

english, 2011

11

It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS

Ragu Ramanathan, Mohammed Jemal, Suma Ramagiri, Yuan-Qing Xia, W. Griffith Humpreys, Timothy Olah, Walter A. Korfmacher

Journal:

Journal of Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 326 KB

english, 2011

12

2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 – PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies’ inputs on bioanalysis, biomarkers and immunogenicity)

Neubert, Hendrik, Olah, Timothy, Lee, Anita, Fraser, Stephanie, Dodge, Robert, Laterza, Omar, Szapacs, Matthew, Alley, Stephen C, Saad, Ola M, Amur, Shashi, Chen, Linzhi, Cherry, Elana, Cho, Seongeun

Journal:

Year:

2018

Language:

english

File:

PDF, 713 KB

english, 2018

13

Full-scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC–HRMS for the quantitation of prednisone and prednisolone in human plasma

Eliza N. Fung, Yuan-qing Xia, Anne-Francoise Aubry, Jianing Zeng, Timothy Olah, Mohammed Jemal

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 801 KB

english, 2011

14

Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum

Zhang, Hongwei, Xiao, Qing, Xin, Baomin, Trigona, Wendy, Tymiak, Adrienne A., Dongre, Ashok R., Olah, Timothy V.

Journal:

Rapid Communications in Mass Spectrometry

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

15

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

Rebbeck, Timothy R., Friebel, Tara M., Friedman, Eitan, Hamann, Ute, Huo, Dezheng, Kwong, Ava, Olah, Edith, Olopade, Olufunmilayo I., Solano, Angela R., Teo, Soo-Hwang, Thomassen, Mads, Weitzel, Jeffr

Journal:

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

16

Targeted quantitative bioanalysis in plasma using liquid chromatography/high-resolution accurate mass spectrometry: an evaluation of global selectivity as a function of mass resolving power and extraction window, with comparison of centroid and profile modes

Yuan-Qing Xia, Jim Lau, Timothy Olah, Mohammed Jemal

Journal:

Rapid Communications in Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 1.72 MB

english, 2011

17

DBS sampling can be used to stabilize prodrugs in drug discovery rodent studies without the addition of esterase inhibitors

D’Arienzo, Celia J, Ji, Qin C, Discenza, Lorell, Cornelius, Georgia, Hynes, John, Cornelius, Lyndon, Santella, Joseph B, Olah, Timothy

Journal:

Year:

2010

Language:

english

File:

PDF, 855 KB

english, 2010

18

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group

Evans, Christopher, Arnold, Mark, Bryan, Peter, Duggan, Jeffrey, James, Christopher A, Li, Wenkui, Lowes, Steve, Matassa, Luca, Olah, Timothy, Timmerman, Philip, Wang, Xiaomin, Wickremsinhe, Enaksha,

Journal:

The AAPS Journal

Year:

2015

Language:

english

File:

PDF, 418 KB

english, 2015

19

Location of Increased Serum Survival Gene and Selected Virulence Traits on a Conjugative R Plasmid in an Avian Escherichia coli Isolate

Johnson, Timothy J., Giddings, Catherine W., Horne, Shelley M., Gibbs, Penelope S., Wooley, Richard E., Skyberg, Jerod, Olah, Pam, Kercher, Ronda, Sherwood, Julie S., Foley, Steven L., Nolan, Lisa K.

Journal:

Year:

2002

Language:

english

File:

PDF, 314 KB

english, 2002

20

COMMISSION 27: VARIABLE STARS

Handler, Gerald, Pollard, Karen R., Kawaler, Steven, Cunha, Margarida S., Olah, Katalin, Kolenberg, Katrien, Jeffery, C. Simon, Catelan, Márcio, Eyer, Laurent, Bedding, Timothy R., Kepler, S. O., Mkrt

Journal:

Proceedings of the International Astronomical Union

Year:

2011

Language:

english

File:

PDF, 78 KB

english, 2011

21

A Persistent α-Fluorocarbanion and Its Analogues: Preparation, Characterization, and Computational Study

G. K. Surya Prakash, Fang Wang, Nan Shao, Thomas Mathew, Golam Rasul, Ralf Haiges, Timothy Stewart, George A. Olah

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

22

A Persistent α-Fluorocarbanion and Its Analogues: Preparation, Characterization, and Computational Study

G. K. Surya Prakash, Fang Wang, Nan Shao, Thomas Mathew, Golam Rasul, Ralf Haiges, Timothy Stewart, George A. Olah

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 500 KB

english, 2009

23

High-throughput chiral analysis of albuterol enantiomers in dog plasma using on-line sample extraction/polar organic mode chiral liquid chromatography with tandem mass spectrometric detection

Steven T. Wu, Jinsong Xing, Atsu Apedo, David B. Wang-Iverson, Timothy V. Olah, Adrienne A. Tymiak, Ning Zhao

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 124 KB

english, 2004

24

Application and challenges in using LC–MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery

Zheng, Joanna, Mehl, John, Zhu, Yongxin, Xin, Baomin, Olah, Timothy

Journal:

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

25

Ion suppression and cannulation locking solutions

Morgan, Daniel G, Olah, Timothy V

Journal:

Year:

2009

Language:

english

File:

PDF, 843 KB

english, 2009

26

Increasing high-throughput Discovery bioanalysis using automated selected reaction monitoring compound optimization, ultra-high-pressure liquid chromatography, and single-step sample preparation workflows

James Smalley, Baomin Xin, Timothy V. Olah

Journal:

Rapid Communications in Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 334 KB

english, 2009

27

A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies

Michael T. Furlong, Zheng Ouyang, Steven Wu, James Tamura, Timothy Olah, Adrienne Tymiak, Mohammed Jemal

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

28

What is next for dried blood spots?

Ji, Qin C, Liu, Guowen, D’Arienzo, Celia J, Olah, Timothy V, Arnold, Mark E

Journal:

Year:

2012

Language:

english

File:

PDF, 601 KB

english, 2012

29

A peptide immunoaffinity LCâMS/MS strategy for quantifying the GPCR protein, S1PR1 in human colon biopsies

Zhang, Hongwei, Ciccimaro, Eugene, Zalaznick, Jacob, Sleczka, Bogdan G, Menard, Laurence, Olah, Timothy V, Shipkova, Petia

Journal:

Year:

2020

File:

PDF, 1007 KB

2020

30

Combinatorial diversification of indinavir: in vivo mixture dosing of an HIV protease inhibitor library

Thomas A Rano, Yuan Cheng, Tracy T Huening, Fengqi Zhang, William A Schleif, Lori Gabryelski, David B Olsen, Lawrence C Kuo, Jiunn H Lin, Xin Xu, Timothy V Olah, Debra A McLoughlin, Richard King, Kevi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 310 KB

english, 2000

31

Plasma timolol concentrations of timolol maleate: timolol gel-forming solution (TIMOPTIC-XE®) once daily versus timolol maleate ophthalmic solution twice daily

Arthur H. Shedden, Jean Laurence, Andrea Barrish, Timothy V. Olah

Journal:

Documenta Ophthalmologica

Year:

2001

Language:

english

File:

PDF, 55 KB

english, 2001

32

Addressing the need for biomarker liquid chromatography/mass spectrometry assays: A protocol for effective method development for the bioanalysis of endogenous compounds in cerebrospinal fluid

Benitex, Yulia, McNaney, Colleen A., Luchetti, David, Schaeffer, Eric, Olah, Timothy V., Morgan, Daniel G., Drexler, Dieter M.

Journal:

Rapid Communications in Mass Spectrometry

Year:

2013

Language:

english

File:

PDF, 406 KB

english, 2013

33

Analysis of l-serine-O-phosphate in cerebrospinal spinal fluid by derivatization–liquid chromatography/mass spectrometry

McNaney, Colleen A., Benitex, Yulia, Luchetti, David, Labasi, Jeffrey M., Olah, Timothy V., Morgan, Daniel G., Drexler, Dieter M.

Journal:

Analytical Biochemistry

Year:

2014

Language:

english

File:

PDF, 327 KB

english, 2014

34

Effect of mobile phase pH, aqueous-organic ratio, and buffer concentration on electrospray ionization tandem mass spectrometric fragmentation patterns: implications in liquid chromatography/tandem mass spectrometric bioanalysis

Jian Wang, Anne Aubry, Mark S. Bolgar, Huidong Gu, Timothy V. Olah, Mark Arnold, Mohammed Jemal

Journal:

Rapid Communications in Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 568 KB

english, 2010

35

Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies

Shujie J. Wang, Steven T. Wu, Jochem Gokemeijer, Aberra Fura, Murli Krishna, Paul Morin, Guodong Chen, Karen Price, David Wang-Iverson, Timothy Olah, Russell Weiner, Adrienne Tymiak, Mohammed Jemal

Journal:

Analytical and Bioanalytical Chemistry

Year:

2012

Language:

english

File:

PDF, 325 KB

english, 2012

36

The integration of ligand binding and LC-MS-based assays into bioanalytical strategies for protein analysis

Zhang, Yan J, Olah, Timothy V, Zeng, Jianing

Journal:

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

37

Bioanalysis of endogenous bile acids by LC-MS utilizing stable isotope labeled analogues

Zheng, Joanna J., Shields, Eric E., Snow, Kimberly J., Nelson, David M., Olah, Timothy V., Reily, Michael D., Robertson, Donald G., Shipkova, Petia A., Stryker, Steven A., Xin, Baomin, Drexler, Dieter

Journal:

Analytical Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

38

Antibody Drug-Target Engagement Measurement in Tissue Using Quantitative Affinity Extraction Liquid Chromatography–Mass Spectrometry: Method Development and Qualification

Ciccimaro, Eugene, Zhu, Yongxin, Ostanin, Dmitry, Suchard, Suzanne, MacGuire, Jamus, Xiao, Qing, Dongre, Ashok, Chimalakonda, Anjaneya, Olah, Timothy, Shipkova, Petia

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

39

COMMISSION 27: VARIABLE STARS

Kawaler, Steven D., Handler, Gerald, Aerts, Conny, Bedding, Timothy R., Catelán, Márcio, Cunha, Margarida, Eyer, Laurent, Jeffery, C. Simon, Martinez, Peter, Olah, Katalin, Pollard, Karen, Somasundara

Journal:

Proceedings of the International Astronomical Union

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

40

Protein Biomarker Quantification by Immunoaffinity Liquid ChromatographyâTandem Mass Spectrometry: Current State and Future Vision

Neubert, Hendrik, Shuford, Christopher M, Olah, Timothy V, Garofolo, Fabio, Schultz, Gary A, Jones, Barry R, Amaravadi, Lakshmi, Laterza, Omar F, Xu, Keyang, Ackermann, Bradley L

Journal:

Clinical Chemistry

Year:

2020

File:

PDF, 739 KB

2020

41

Strategy to Improve the Quantitative LC-MS Analysis of Molecular Ions Resistant to Gas-Phase Collision Induced Dissociation: Application to Disulfide-Rich Cyclic Peptides

Ciccimaro, Eugene, Ranasinghe, Asoka, D’Arienzo, Celia, Xu, Carrie, Onorato, Joelle, Drexler, Dieter M., Josephs, Jonathan L., Poss, Michael, Olah, Timothy

Journal:

Analytical Chemistry

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

42

The Simultaneous Determination of Mixtures of Drug Candidates by Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry as an In Vivo Drug Screening Procedure

Timothy V. Olah, Debra A. McLoughlin, John D. Gilbert

Journal:

Rapid Communications in Mass Spectrometry

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

43

Development of a quantitative LC–MS/MS analytical method coupled with turbulent flow chromatography for digoxin for the in vitro P-gp inhibition assay

James Smalley, Anthony M. Marino, Baomin Xin, Timothy Olah, Praveen V. Balimane

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 530 KB

english, 2007

44

Pellet digestion: a simple and efficient sample preparation technique for LC–MS/MS quantification of large therapeutic proteins in plasma

Ouyang, Zheng, Furlong, Michael T, Wu, Steven, Sleczka, Bogdan, Tamura, James, Wang, Haiqing, Suchard, Suzanne, Suri, Anish, Olah, Timothy, Tymiak, Adrienne, Jemal, Mohammed

Journal:

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

45

Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry

Benitex, Yulia, Luan, Fu-Ni, Shields, Eric, McNaney, Colleen A, Morgan, Daniel G, Olah, Timothy V, Drexler, Dieter M

Journal:

Year:

2014

Language:

english

File:

PDF, 869 KB

english, 2014

46

Quantification of human mAbs in mouse tissues using generic affinity enrichment procedures and LC–MS detection

Sleczka, Bogdan G, Mehl, John T, Shuster, David J, Lewis, Katherine E, Moore, Robin, Vuppugalla, Ragini, Rajendran, Surendran, D'Arienzo, Celia J, Olah, Timothy V

Journal:

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

47

LC–MS/MS multiplexed assay for the quantitation of a therapeutic protein BMS-986089 and the target protein Myostatin

Zhu, Yongxin, D'Arienzo, Celia, Lou, Zhen, Kozhich, Alexander, Madireddi, Malavi, Chimalakonda, Anjaneya, Tymiak, Adrienne, Olah, Timothy V

Journal:

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

48

Ultrahigh-throughput and Chromatography-free Bioanalysis of Polar Analytes with Acoustic Ejection Mass Spectrometry

Wagner, Andrew, Zhang, Jun, Liu, Chang, Covey, Thomas R, Olah, Timothy V., Weller, Harold (Bud) N., Shou, Wilson Z.

Journal:

Analytical Chemistry

Year:

2020

File:

PDF, 651 KB

2020

49

Lymphatic uptake of MK-386, a sterol 5α-reductase inhibitor, from aqueous and lipid formulations

Gloria Y Kwei, Linda B Novak, Lisa H Hettrick, Elisabeth R Reiss, Eva K Fong, Timothy V Olah, Alice E Loper

Journal:

International Journal of Pharmaceutics

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

50

Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS

Ranasinghe, Asoka, Ramanathan, Ragu, Jemal, Mohammed, D’Arienzo, Celia J, Humphreys, W Griffith, Olah, Timothy V

Journal:

Year:

2012

Language:

english

File:

PDF, 2.29 MB

english, 2012

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